Author: Gary Grumbach ,Dareh Gregorian

Background Accumulating evidence has supported the associations between childhood maltreatment and increased risk of depression; however, the underlying mechanisms remain largely unclear. We aimed to explore the potential role of lifestyle factors, personality traits, adult traumas, and social connections in the association between childhood maltreatment and depression. Methods We used a nationwide cohort data from the UK Biobank, involving half a million participants aged 37–73 years, recruited across 22 centers in the UK between 2006 and 2010. Participants with complete information on childhood experiences and who were free of depression were included. The Childhood Trauma Questionnaire was used to calculate…

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